I know of no good way to quantify the value of one person's contribution to science, or indeed any other field of intellectual endeavour. Nevertheless, people often try to do so, and the vast majority of these efforts focus on citation counts. There are many suggestions as to what is the most reliable indicator: total citation count, average citations per paper, or something slightly more sophisticated, like the h-index. Needless to say, all of these have major flaws, and tend to favour scientists who have simply been around for a long time, or who work on popular topics, but I get the impression that such quantities are still sometimes used as an aid in decisions on hiring, tenure etc.
Such issues have been discussed exhaustively on the blogosphere and elsewhere (although I'm too lazy to gather any links), and I don't really have anything new to add. But I did want to point out that, as far as I can tell, accurate citation data often simply aren't available.